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Anti-GABRB3 Antibody

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ABclonal
A10015
Overview
Name: Anti-GABRB3 Antibody
Description: Rabbit polyclonal antibody to GABRB3.
Applications: WB
Dilutions: WB 1:500 - 1:1000
Reactivity: Human
Immunogen: Recombinant protein of human GABRB3
Protein Length: 473
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
Involvement in Disease: Epilepsy, childhood absence 5: A subtype of idiopathic generalized epilepsy characterized by an onset at age 6-7 years, frequent absence seizures (several per day) and bilateral, synchronous, symmetric 3-Hz spike waves on EEG. Tonic-clonic seizures often develop in adolescence. Absence seizures may either remit or persist into adulthood.

Epileptic encephalopathy, early infantile, 43: A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. EIEE43 inheritance is autosomal dominant.
Sequence Similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB3 sub-subfamily.
Cellular Location: Cell junction > Synapse > Postsynaptic cell membrane. Cell membrane. Cytoplasmic vesicle membrane.
UniProt: P28472
Gene ID: 2562
Synonyms: ECA5 Antibody
GABA A Receptor beta 2 + 3 Antibody
GABA A Receptor beta 3 Antibody
GABA alpha receptor beta-2 subunit Antibody
GABA(A) receptor subunit beta-3 Antibody
GABAA receptor beta 2 subunit Antibody
GABAA receptor beta 3 subunit Antibody
GABAA receptor subunit beta 2 Antibody
GABAA receptor subunit beta 3 Antibody
GABR B3 Antibody
GABRB2 Antibody
Gamma aminobutyric acid (GABA) A receptor beta 3 Antibody
Gamma aminobutyric acid receptor subunit beta 2 Antibody
Gamma aminobutyric acid receptor subunit beta 3 Antibody
Gamma-aminobutyric acid receptor subunit beta-3 Antibody
GBRB3_HUMAN Antibody
MGC9051 Antibody

Images
Western Blot - Anti-GABRB3 Antibody from ABclonal (A10015) - Antibody Supply Service
Western blot analysis of extracts of various cells, using GABRB3 antibody.

Product Code - A10015
Size Price Quantity
50µl £148
100µl £243
200µl £372

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