phone icon
+44 (0)1223 298875

Anti-NEDD8 Antibody

file icon Datasheet
ABclonal
A10008
Overview
Name: Anti-NEDD8 Antibody
Description: Mouse monoclonal antibody to NEDD8.
Applications: WB, IHC, ICC, IF, FC
Dilutions: WB 1:500 - 1:2000, IHC 1:50- 1:200, ICC 1:50- 1:200, IF 1:20- 1:100, FC 1:20- 1:50
Reactivity: Human
Immunogen: Recombinant protein of human NEDD8
Protein Length: 81
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Tissue Specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
Sequence Similarities: Belongs to the ubiquitin family.
Post-Translational Modification: Cleavage of precursor form by UCHL3 or SENP8 is necessary for function.
Cellular Location: Nucleus.

Mainly nuclear.
UniProt: Q15843
Gene ID: 4738
Synonyms: FLJ43224 Antibody
MGC104393 Antibody
MGC125896 Antibody
MGC125897 Antibody
NED8 Antibody
NEDD 8 Antibody
NEDD-8 Antibody
NEDD8_HUMAN Antibody
Neddylin Antibody
Neural precursor cell expressed developmentally down regulated 8 Antibody
Neural precursor cell expressed developmentally down regulated gene 8 Antibody
Neural precursor cell expressed developmentally down-regulated protein 8 Antibody
Rub1 Antibody
Ubiquitin like protein Nedd 8 Antibody
Ubiquitin like protein Nedd8 Antibody
Ubiquitin-like protein Nedd8 Antibody

Images
Western Blot - Anti-NEDD8 Antibody from ABclonal (A10008) - Antibody Supply Service
Western blot analysis of extracts of HeLa cells, using NEDD8 antibody.

Product Code - A10008
Size Price Quantity
50µl £199
100µl £307
200µl £452

or
Request a quotation
Contact us directly to order
  • call icon +44 (0)1223 298875
  • +44 (0)1223 281447
  • email icon orders@ab-y-ss.com
Product Quality
  • guarantee icon
  • We promise guaranteed product quality
  • and expert customer service.
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe