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Anti-CTHRC1 Antibody

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ABclonal
A0940
Overview
Name: Anti-CTHRC1 Antibody
Description: Rabbit polyclonal antibody to CTHRC1.
Applications: WB, IHC, FC
Dilutions: WB 1:500 - 1:1000, IHC 1:50 - 1:100, FC 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human CTHRC1
Protein Length: 243
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: May act as a negative regulator of collagen matrix deposition.
Tissue Specificity: Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells.
Involvement in Disease: Barrett esophagus: A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes.
Post-Translational Modification: N-glycosylated.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
UniProt: Q96CG8
Gene ID: 115908
Synonyms: Collagen triple helix repeat containing 1 Antibody
Collagen triple helix repeat containing protein 1 Antibody
Collagen triple helix repeat-containing protein 1 Antibody
CTHR1_HUMAN Antibody
NMTC1 protein Antibody
Protein NMTC1 Antibody

Images
Western Blot - Anti-CTHRC1 Antibody from ABclonal (A0940) - Antibody Supply Service
Western blot analysis of extracts of A375 cell line, using CTHRC1 antibody.

Product Code - A0940
Size Price Quantity
100µl £243
200µl £372

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