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Anti-CANP2 Antibody

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Name: Anti-CANP2 Antibody
Description: Mouse monoclonal antibody to CANP2.
Applications: WB, IHC, FC
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100, FC 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human CAPN2
Protein Length: 700
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
Tissue Specificity: Ubiquitous.
Sequence Similarities: Belongs to the peptidase C2 family.
Cellular Location: Cytoplasm. Cell membrane.

Translocates to the plasma membrane upon Ca(2+) binding.
UniProt: P17655
Gene ID: 824
Synonyms: Calcium activated neutral proteinase Antibody
Calcium activated neutral proteinase 2 Antibody
Calcium-activated neutral protease 2, catalytic subunit Antibody
Calcium-activated neutral proteinase 2 Antibody
CALP80 Antibody
Calpain 2 Antibody
Calpain 2 (m/II) large subunit Antibody
Calpain 2 catalytic subunit Antibody
Calpain 2 large catalytic subunit Antibody
Calpain 2 large subunit Antibody
Calpain 2, large [catalytic] subunit Antibody
Calpain large polypeptide L2 Antibody
Calpain M type Antibody
Calpain M-type Antibody
Calpain-2 catalytic subunit Antibody
Calpain-2 large subunit Antibody
Calpain2 Antibody
CAN2_HUMAN Antibody
CANP 2 Antibody
CANP L2 Antibody
CANPL 2 Antibody
CANPL2 Antibody
CANPml Antibody
Capa2 Antibody
CAPN 2 Antibody
CAPN2 Antibody
FLJ39928 Antibody
M calpain Antibody
M calpin Antibody
M type Antibody
M-calpain Antibody
mCANP Antibody
Millimolar calpain Antibody
Millimolar-calpain Antibody

Western Blot - Anti-CANP2 Antibody from ABclonal (A0900) - Antibody Supply Service
Western blot analysis of extracts of Y79 cells lines, using CAPN2 antibody.

Product Code - A0900
Size Price Quantity
100µl £243
200µl £372

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