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Anti-Moesin Antibody

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ABclonal
A0847
Overview
Name: Anti-Moesin Antibody
Description: Rabbit polyclonal antibody to Moesin.
Applications: WB
Dilutions: WB 1:500 - 1:1000
Reactivity: Human
Immunogen: A synthetic peptide of human MSN
Protein Length: 577
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
Tissue Specificity: In all tissues and cultured cells studied.
Post-Translational Modification: Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures. Phosphorylation by ROCK2 suppresses the head-to-tail association of the N-terminal and C-terminal halves resulting in an opened conformation which is capable of actin and membrane-binding (By similarity). Phosphorylation on Thr-558 by STK10 negatively regulates lymphocyte migration and polarization.
Cellular Location: Cell membrane. Cytoplasm > Cytoskeleton. Apical cell membrane. Cell projection > Microvillus membrane.

Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment.
UniProt: P26038
Gene ID: 4478
Synonyms: Epididymis luminal protein 70 Antibody
HEL70 Antibody
Membrane organizing extension spike protein Antibody
Membrane-organizing extension spike protein Antibody
Moesin (phospho T558) Antibody
Moesin/anaplastic lymphoma kinase fusion protein Antibody
MOES_HUMAN Antibody
Msn Antibody
MSN/ALK fusion Antibody

Images
Western Blot - Anti-Moesin Antibody from ABclonal (A0847) - Antibody Supply Service
Western blot analysis of extracts of Jurkat cells tissue, using MSN antibody.

Product Code - A0847
Size Price Quantity
100µl £243
200µl £372

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