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Anti-ERCC1 Antibody

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ABclonal
A0777
Overview
Name: Anti-ERCC1 Antibody
Description: Mouse monoclonal antibody to ERCC1.
Applications: WB
Dilutions: WB 1:500 - 1:2000
Reactivity: Human
Immunogen: A synthetic peptide of human ERCC1
Protein Length: 297
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Involvement in Disease: Cerebro-oculo-facio-skeletal syndrome 4: A disorder of prenatal onset characterized by microcephaly, congenital cataracts, facial dysmorphism, neurogenic arthrogryposis, growth failure and severe psychomotor retardation. COFS is considered to be part of the nucleotide-excision repair disorders spectrum that include also xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome.
Sequence Similarities: Belongs to the ERCC1/RAD10/SWI10 family.
Cellular Location: Nucleus.
UniProt: P07992
Gene ID: 2067
Synonyms: COFS 4 Antibody
COFS4 Antibody
DNA excision repair protein ERCC 1 Antibody
DNA excision repair protein ERCC-1 Antibody
DNA excision repair protein ERCC1 Antibody
ERCC 1 Antibody
ERCC1_HUMAN Antibody
Excision repair cross complementation group 1 Antibody
Excision repair cross complementing 1 Antibody
Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 Antibody
Excision repair protein Antibody
RAD 10 Antibody
RAD10 Antibody
UV 20 Antibody
UV20 Antibody

Images
Western Blot - Anti-ERCC1 Antibody from ABclonal (A0777) - Antibody Supply Service
Western blot analysis of extracts of MCF7 cells tissue, using ERCC1 antibody.

Product Code - A0777
Size Price Quantity
100µl £243
200µl £372

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