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Anti-BMP7 Antibody

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ABclonal
A0722
Details
Description: Rabbit polyclonal antibody to BMP7.
Category: Primary Antibodies
Applications: WB, IHC, IF
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: P18075
Gene ID: 655
Immunogen: A synthetic peptide of human BMP7
Protein Length: 431
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: BMP7; OP1; Bone morphogenetic protein 7; Osteogenic protein 1; INN=Eptotermin alfa; Flags: Precursor
Purification: Affinity purification
Background: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity.
Storage: Store at 4℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:1000, IHC 1:50 - 1:100, IF 1:20 - 1:50

Target (Information from UniProt)
Function: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Tissue Specificity: Expressed in the kidney and bladder. Lower levels seen in the brain.
Sequence Similarities: Belongs to the TGF-beta family.
Post-Translational Modification: Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms.
Cellular Location: Secreted.

Images
Western Blot - Anti-BMP7 Antibody from ABclonal (A0722) - Antibody Supply Service
Western blot analysis of extracts of 293 cell line, using BMP7 antibody.

Product Code - A0722
Size Price Quantity
100µl £243
200µl £372

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