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Anti-TJP1 Antibody

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ABclonal
A0659
Overview
Name: Anti-TJP1 Antibody
Description: Rabbit polyclonal antibody to TJP1.
Applications: WB, IHC, IF, IP, FC
Dilutions: WB 1:200 - 1:500, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:20 - 1:50, FC 1:20 - 1:50
Reactivity: Human
Immunogen: Recombinant Protein of human TJP1
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Tissue Specificity: The alpha-containing isoform is found in most epithelial cell junctions. The short isoform is found both in endothelial cells and the highly specialized epithelial junctions of renal glomeruli and Sertoli cells of the seminiferous tubules.
Sequence Similarities: Belongs to the MAGUK family.
Post-Translational Modification: Phosphorylated. Dephosphorylated by PTPRJ.
Cellular Location: Cell membrane. Cell junction > Tight junction. Cell junction. Cell junction > Gap junction.

Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells.
UniProt: Q07157
Gene ID: 7082
Synonyms: Tight junction protein 1 Antibody
Tight junction protein ZO-1 Antibody
Tight junction protein ZO1 Antibody
zo-1 Antibody
Zo1 Antibody
ZO1 tight junction protein Antibody
ZO1_HUMAN Antibody
Zona occludens 1 Antibody
Zona occludens 1 protein Antibody
Zona occludens protein 1 Antibody
Zonula occludens 1 protein Antibody
Zonula occludens protein 1 Antibody

Images
Western Blot - Anti-TJP1 Antibody from ABclonal (A0659) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using TJP1 antibody.

Product Code - A0659
Size Price Quantity
50µl £148
100µl £243
200µl £372

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