Anti-Hexokinase I AntibodyDatasheet
|Name:||Anti-Hexokinase I Antibody|
|Description:||Rabbit polyclonal antibody to Hexokinase I.|
|Dilutions:||WB 1:500 - 1:1000, IHC 1:50 - 1:100|
|Immunogen:||A synthetic peptide of human HK1|
|Formulation:||PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Storage:||Store at 4℃. Avoid freeze / thaw cycles.|
Target (Information from UniProt)
|Tissue Specificity:||Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.|
|Involvement in Disease:||Hexokinase deficiency: Rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature.
Neuropathy, hereditary motor and sensory, Russe type: An autosomal recessive progressive complex peripheral neuropathy characterized by onset in the first decade of distal lower limb weakness and muscle atrophy resulting in walking difficulties. Distal impairment of the upper limbs usually occurs later, as does proximal lower limb weakness. There is distal sensory impairment, with pes cavus and areflexia. Laboratory studies suggest that it is a myelinopathy resulting in reduced nerve conduction velocities in the demyelinating range as well as a length-dependent axonopathy.
|Sequence Similarities:||Belongs to the hexokinase family.|
|Cellular Location:||Mitochondrion outer membrane.
Its hydrophobic N-terminal sequence may be involved in membrane binding.
Brain form hexokinase Antibody
EC 220.127.116.11 Antibody
Glycolytic enzyme Antibody
Hexokinase 1 Antibody
Hexokinase PI Antibody
Hexokinase type I Antibody
Hexokinase, tumor isozyme Antibody
HK I Antibody
HK1 tb Antibody
Western blot analysis of extracts of 293T cells, using HK1 antibody.