phone icon
+44 (0)1223 298875

Anti-RAC2 Antibody

file icon Datasheet
ABclonal
A0509
Overview
Name: Anti-RAC2 Antibody
Description: Rabbit polyclonal antibody to RAC2.
Applications: WB
Dilutions: WB 1:500 - 1:1000, IF 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human RAC2
Protein Length: 192
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
Tissue Specificity: Hematopoietic specific.
Involvement in Disease: Neutrophil immunodeficiency syndrome: An immunodeficiency syndrome due to defective neutrophils. Affected individuals present with leukocytosis, neutrophilia, severe recurrent bacterial infections and poor wound healing.
Sequence Similarities: Belongs to the small GTPase superfamily. Rho family.
Post-Translational Modification: (Microbial infection) Glycosylated at Tyr-32 by Photorhabdus asymbiotica toxin PAU_02230. Mono-O-GlcNAcylation by PAU_02230 inhibits downstream signaling by an impaired interaction with diverse regulator and effector proteins of Rac and leads to actin disassembly.
Cellular Location: Cytoplasm.

Membrane-associated when activated.
UniProt: P15153
Gene ID: 5880
Synonyms: Cell migration-inducing gene 5 protein Antibody
EN 7 Antibody
EN-7 Antibody
EN7 Antibody
GX Antibody
HSPC 022 Antibody
HSPC022 Antibody
MIG5 Antibody
p21 Rac 2 Antibody
p21 Rac2 Antibody
p21-Rac1 Antibody
p21-Rac2 Antibody
p21-Rac3 Antibody
p21Rac2 Antibody
RAC 2 Antibody
RAC1 Antibody
Rac1 + Rac2 + Rac3 Antibody
RAC2_HUMAN Antibody
RAC3 Antibody
Ras related C3 botulinum toxin substrate 2 Antibody
Ras related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2 Antibody
Ras related C3 botulinum toxin substrate 3 Antibody
Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac2) Antibody
Ras-like protein TC25 Antibody
Ras-related C3 botulinum toxin substrate 1 Antibody
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Antibody
Ras-related C3 botulinum toxin substrate 2 Antibody
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) Antibody
Ras-related C3 botulinum toxin substrate 3 Antibody
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) Antibody
Rho family small GTP binding protein Rac 2 Antibody
Rho family small GTP binding protein Rac2 Antibody
Small G protein Antibody
TC25 Antibody

Images
Western Blot - Anti-RAC2 Antibody from ABclonal (A0509) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using RAC2 antibody.

Product Code - A0509
Size Price Quantity
100µl £243
200µl £372

or
Request a quotation
Contact us directly to order
  • call icon +44 (0)1223 298875
  • +44 (0)1223 281447
  • email icon orders@ab-y-ss.com
Product Quality
  • guarantee icon
  • We promise guaranteed product quality
  • and expert customer service.
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe