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Anti-ENG Antibody

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ABclonal
A0391
Overview
Name: Anti-ENG Antibody
Description: Rabbit polyclonal antibody to ENG.
Applications: WB
Dilutions: WB 1:200 - 1:2000
Reactivity: Human
Immunogen: A synthetic peptide of human ENG
Protein Length: 658
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
Tissue Specificity: Endoglin is restricted to endothelial cells in all tissues except bone marrow.
Involvement in Disease: Telangiectasia, hereditary hemorrhagic, 1: A multisystemic vascular dysplasia leading to dilation of permanent blood vessels and arteriovenous malformations of skin, mucosa, and viscera. The disease is characterized by recurrent epistaxis and gastro-intestinal hemorrhage. Visceral involvement includes arteriovenous malformations of the lung, liver, and brain.
Cellular Location: Membrane.
UniProt: P17813
Gene ID: 2022
Synonyms: AI528660 Antibody
AI662476 Antibody
CD 105 Antibody
CD105 Antibody
CD105 antigen Antibody
EGLN_HUMAN Antibody
En Antibody
END Antibody
Endoglin Antibody
Engrailed Antibody
Engrailed and Invected Antibody
Engrailed/Invected Antibody
FLJ41744 Antibody
HHT1 Antibody
Homeobox protein invected Antibody
Inv Antibody
Invected Antibody
ORW Antibody
ORW1 Antibody
Osler Rendu Weber syndrome 1 Antibody
RP11 228B15.2 Antibody
S-endoglin Antibody
SN6 Antibody

Images
Western Blot - Anti-ENG Antibody from ABclonal (A0391) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using ENG antibody.

Product Code - A0391
Size Price Quantity
100µl £243
200µl £372

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