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Anti-Adiponectin Antibody

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ABclonal
A0328
Overview
Name: Anti-Adiponectin Antibody
Description: Rabbit polyclonal antibody to Adiponectin.
Applications: WB, IP
Dilutions: WB 1:1000 - 1:2000, IP 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human ADIPOQ
Protein Length: 244
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Tissue Specificity: Synthesized exclusively by adipocytes and secreted into plasma.
Involvement in Disease: Adiponectin deficiency: A condition that results in very low concentrations of plasma adiponectin.

Diabetes mellitus, non-insulin-dependent: A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Post-Translational Modification: Hydroxylated Lys-33 was not identified in PubMed:16497731, probably due to poor representation of the N-terminal peptide in mass fingerprinting.
Cellular Location: Secreted.
UniProt: Q15848
Gene ID: 9370
Synonyms: 30 kDa adipocyte complement related protein Antibody
30 kDa adipocyte complement-related protein Antibody
ACDC Antibody
ACRP30 Antibody
Adipocyte Antibody
adipocyte C1Q and collagen domain containing Antibody
Adipocyte C1q and collagen domain containing protein Antibody
Adipocyte complement related 30 kDa protein Antibody
Adipocyte complement related protein of 30 kDa Antibody
Adipocyte complement-related 30 kDa protein Antibody
adipocyte-specific secretory protein Antibody
Adiponectin precursor Antibody
adiponectin, C1Q and collagen domain containing Antibody
Adipoq Antibody
adipose most abundant gene transcript 1 Antibody
Adipose most abundant gene transcript 1 protein Antibody
Adipose specific collagen like factor Antibody
ADIPO_HUMAN Antibody
ADIPQTL1 Antibody
ADPN Antibody
APM 1 Antibody
apM-1 Antibody
APM1 Antibody
C1q and collagen domain-containing protein Antibody
GBP28 Antibody
Gelatin binding protein Antibody
Gelatin binding protein 28 Antibody
Gelatin-binding protein Antibody
HPC 1 Antibody
p35 1 Antibody
STX1 Antibody
STX1A Antibody
STX1B1 Antibody
STX1B2 Antibody
Syntaxin 1A + Syntaxin 1B2 Antibody

Images
Western Blot - Anti-Adiponectin Antibody from ABclonal (A0328) - Antibody Supply Service
Western blot analysis of L02 cell and HeLa cell lysate using ADIPOQ antibody.

Product Code - A0328
Size Price Quantity
50µl £243
100µl £372
200µl £565

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