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Anti-TRADD Antibody

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Name: Anti-TRADD Antibody
Description: Rabbit polyclonal antibody to TRADD.
Applications: WB, IHC, IF, FC
Dilutions: WB 1:500 - 1:1000, IHC 1:50 - 1:100, IF 1:20 - 1:50, FC 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human TRADD
Protein Length: 312
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Tissue Specificity: Found in all examined tissues.
Cellular Location: Nucleus. Cytoplasm. Cytoplasm > Cytoskeleton.

Shuttles between the cytoplasm and the nucleus.
UniProt: Q15628
Gene ID: 8717
Synonyms: 9130005N23Rik Antibody
AA930854 Antibody
TNFR1 associated DEATH domain protein Antibody
TNFR1-associated DEATH domain protein Antibody
TNFRSF1A associated via death domain Antibody
TNFRSF1A-associated via death domain Antibody
Tumor necrosis factor receptor type 1 associated DEATH domain protein Antibody
Tumor necrosis factor receptor type 1-associated DEATH domain protein Antibody

Western Blot - Anti-TRADD Antibody from ABclonal (A0183) - Antibody Supply Service
Western blot analysis of extracts of HeLa cells, using TRADD antibody.

Product Code - A0183
Size Price Quantity
100µl £243
200µl £372

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