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Anti-GFAP Antibody

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Name: Anti-GFAP Antibody
Description: Mouse monoclonal antibody to GFAP.
Applications: WB, IHC, IF
Dilutions: WB 1:500 - 1:1000, IHC 1:50 - 1:100, IF 1:20 - 1:50
Reactivity: Human
Immunogen: Recombinant protein of human GFAP
Protein Length: 432
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Tissue Specificity: Expressed in cells lacking fibronectin.
Involvement in Disease: Alexander disease: A rare disorder of the central nervous system. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death within the first decade. Infants with Alexander disease develop a leukodystrophy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course. Histologically, Alexander disease is characterized by Rosenthal fibers, homogeneous eosinophilic inclusions in astrocytes.
Sequence Similarities: Belongs to the intermediate filament family.
Post-Translational Modification: Phosphorylated by PKN1.
Cellular Location: Cytoplasm.

Associated with intermediate filaments.
UniProt: P14136
Gene ID: 2670
Synonyms: wu:fb34h11 Antibody
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Western Blot - Anti-GFAP Antibody from ABclonal (A0014) - Antibody Supply Service
Western blot analysis of extracts of MCF7 cells, using GFAP antibody.

Product Code - A0014
Size Price Quantity
100µl £243
200µl £372

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