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Anti-FGF2 (bFGF) Antibody

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Absea Biotechnology
030304G11
Overview
Name: Anti-FGF2 (bFGF) Antibody
Description: Mouse monoclonal (KT1) antibody to FGF2 (bFGF).
Applications: ELISA, WB
Reactivity: Human
Immunogen: Recombinant human bFGF.
Host: Mouse
Clonality: Monoclonal
Clone: KT1
Isotype: IgG1
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target (Information from UniProt)
Function: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis (PubMed:23469107).
Tissue Specificity: Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.
Sequence Similarities: Belongs to the heparin-binding growth factors family.
Post-Translational Modification: Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion.
Cellular Location: Secreted. Nucleus.

Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57.
UniProt: P09038
Gene ID: 2247
Synonyms: Basic fibroblast growth factor Antibody
Basic fibroblast growth factor bFGF Antibody
BFGF Antibody
FGF 13 Antibody
FGF 2 Antibody
FGF B Antibody
FGF-13 Antibody
FGF-2 Antibody
FGF13 Antibody
FGF13_HUMAN Antibody
FGF2 basic Antibody
FGF2_HUMAN Antibody
FGFB Antibody
FHF 2 Antibody
FHF-2 Antibody
FHF2 Antibody
Fibroblast growth factor 13 Antibody
Fibroblast growth factor 2 Antibody
Fibroblast growth factor 2 (basic) Antibody
Fibroblast growth factor homologous factor 2 Antibody
Fibroblast growth factor, basic Antibody
HBGF 2 Antibody
HBGF-2 Antibody
HBGF2 Antibody
HBGH 2 Antibody
HBGH2 Antibody
Heparin binding growth factor 2 precursor Antibody
Heparin-binding growth factor 2 Antibody
OTTHUMP00000024143 Antibody
OTTHUMP00000024144 Antibody
Prostatropin Antibody

Images
Western Blot - Anti-FGF2 (bFGF) Antibody from Absea Biotechnology (030304G11) - Antibody Supply Service
Western blotting result.
Sandwich ELISA - Anti-FGF2 (bFGF) Antibody from Absea Biotechnology (030304G11) - Antibody Supply Service
Sandwich ELISA using KT1 coated plate and HRP conjugated KT49.

Product Code - 030304G11
Size Price Quantity
100µg £178
200µg £259
1mg £682

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