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Anti-IL11 Antibody

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Absea Biotechnology
030112A12
Details
Description: Mouse monoclonal (KT62) antibody to IL11
Category: Primary Antibodies
Applications: ELISA
Host: Mouse
Clonality: Monoclonal
Clone: KT62
Isotype: IgG1
Conjugate: Unconjugated
UniProt: P20809
Gene ID: 3589
Antigen: IL11
Antigen Species: Human
Uniprot Protein Name: Recommended name: Interleukin-11 Short name=IL-11 Alternative name(s): Adipogenesis inhibitory factor Short name=AGIF INN=Oprelvekin
Uniprot Gene Name: Name: IL11
Amino Acid Start: 23
Amino Acid End: 199
Protein Length: 176

Target (Information from UniProt)
Function: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Sequence Similarities: Belongs to the IL-6 superfamily.
Cellular Location: Secreted.

Product Code - 030112A12
Size Price Quantity
100µg £178
200µg £259
1mg £682

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