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Anti-EGF Antibody

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Absea Biotechnology
030106B08
Details
Description: Mouse monoclonal (KT57) antibody to EGF
Category: Primary Antibodies
Applications: ELISA, WB, sELISA
Host: Mouse
Clonality: Monoclonal
Clone: KT57
Isotype: IgG1
Conjugate: Unconjugated
UniProt: P01133
Gene ID: 1950
Antigen: EGF
Antigen Species: Human
Uniprot Protein Name: Recommended name: Pro-epidermal growth factor Short name=EGF
Uniprot Gene Name: Name: EGF
Amino Acid Start: 971
Amino Acid End: 1021
Protein Length: 51

Target (Information from UniProt)
Function: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
Tissue Specificity: Expressed in kidney, salivary gland, cerebrum and prostate.
Involvement in Disease: Hypomagnesemia 4: A disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to moderate psychomotor retardation, and brisk tendon reflexes.
Post-Translational Modification: O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
Cellular Location: Membrane.

Product Code - 030106B08
Size Price Quantity
100µg £178
200µg £259
1mg £682

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