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Anti-AGE Antibody

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Name: Anti-AGE Antibody
Description: Rabbit polyclonal antibody to AGE.
Specificity: Advanced Glycation End Products (AGE), cross-reactivity BSA and HSA <1%.
Applications: ELISA
Immunogen: Advanced Glycation End Products /BSA/HSA.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: ~ 5 mg/ml
Product Form: Liquid
Formulation: Protein A affinity purified IgG in PBS 0.05 M, pH 7.15, 0.85% NaCl, and 0.05% sodium azide.
Storage: Short term 4°C, long term -20°C.

Background: Long-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE) which are characterized by fluorescence, brown color and inter- and intra-molecular cross-linking. Recent immunological studies using anti-AGE antibodies demonstrated the presence of AGE in human lens, renal proximal tubules in patients with diabetic nephropathy and chronic renal failure, atherosclerotic lesions of arterial walls, ß2-microglobulin of carpal tunnel amyloid fibril deposits in patients with hemodialysis-related amyloidosis and brain tissues of patients with Alzheimer's disease. These results suggested the potential role of AGE in normal aging and age-enhanced disease processes.
Synonyms: Advanced glycation end products Antibody
AGEs Antibody
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N acetyl D glucosamine 2 epimerase Antibody
N-acetyl-D-glucosamine 2-epimerase Antibody
N-acylglucosamine 2-epimerase Antibody
RBP Antibody
RENBP Antibody
Renin binding protein Antibody
Renin-binding protein Antibody
RnBP Antibody

Product Code - AGE102-1.0
Size Price Quantity
1mg £659

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