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Anti-EGF Antibody

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Absea Biotechnology
030105B03
Overview
Name: Anti-EGF Antibody
Description: Mouse monoclonal (KT2) antibody to EGF.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Recombinant human EGF.
Host: Mouse
Clonality: Monoclonal
Clone: KT2
Isotype: IgG2a
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target (Information from UniProt)
Function: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
Tissue Specificity: Expressed in kidney, salivary gland, cerebrum and prostate.
Involvement in Disease: Hypomagnesemia 4: A disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to moderate psychomotor retardation, and brisk tendon reflexes.
Post-Translational Modification: O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
Cellular Location: Membrane.
UniProt: P01133
Gene ID: 1950
Synonyms: Beta urogastrone Antibody
EGF latrophilin and seven transmembrane domain containing 1 Antibody
EGF TM7 latrophilin related protein Antibody
EGF, latrophilin and seven transmembrane domain-containing protein 1 Antibody
EGF-TM7-latrophilin-related protein Antibody
EGFTM7 latrophilin related protein Antibody
EGF_HUMAN Antibody
ELTD 1 Antibody
ELTD1 Antibody
ELTD1_HUMAN Antibody
Epidermal growth factor Antibody
ETL Antibody
ETL protein Antibody
HOMG4 Antibody
KPG_003 Antibody
latrophilin and seven transmembrane domain-containing protein 1 Antibody
OTTHUMP00000219721 Antibody
OTTHUMP00000219722 Antibody
Pro epidermal growth factor Antibody
URG Antibody
Urogastrone Antibody
zgc:63629 Antibody

Product Code - 030105B03
Size Price Quantity
100µg £178
200µg £259
1mg £682

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