Anti-C3Orf34 Antibody (Biotin)
|Name:||Anti-C3Orf34 Antibody (Biotin)|
|Description:||Rabbit polyclonal antibody to C3Orf34 (Biotin)|
|Applications:||DB, ELISA, WB|
|Dilutions:||DB: 1:2,000; ELISA: 1:2,000; Western Blot: 1:500-1:1,000|
|Immunogen:||Synthetic peptide taken within amino acid region 120-170 on human Chromosome open reading frame 34 protein.|
|Storage:||-20⁰C for long term storage|
Target (Information from UniProt)
|Involvement in Disease:||Morbid obesity and spermatogenic failure: An autosomal recessive morbid obesity syndrome characterized by hypertension, fatty liver disease, insulin resistance, and decreased sperm counts. Variable clinical manifestations are early coronary artery disease with myocardial infarction before 45 years of age, type II diabetes mellitus, and intellectual disability. Morbid obese individuals are defined as having a BMI greater than 40.|
|Sequence Similarities:||Belongs to the CEP19 family.|
|Cellular Location:||Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome > Centriole. Cytoplasm > Cytoskeleton > Spindle pole. Cytoplasm > Cytoskeleton > Cilium basal body.
Associates with the mother centriole in early interphase (PubMed:21399614). Localizes to spindle poles during mitosis, and to distinct foci oriented towards the midbody at telophase (PubMed:21399614).
|Synonyms:||Chromosome 3 open reading frame 34 Antibody