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Anti-Syndecan-1 Antibody (FITC)

FabGennix
SYND1.112-FITC
Overview
Name: Anti-Syndecan-1 Antibody (FITC)
Description: Rabbit polyclonal antibody to Syndecan-1 (FITC)
Applications: ELISA, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: C-epitope synthetic peptide taken within amino acid region 250-350 on human Syndecan-1 protein.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: FITC
Concentration: 0.55-0.61 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Sequence Similarities: Belongs to the syndecan proteoglycan family.
Post-Translational Modification: Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Cellular Location: Membrane. Secreted. Secreted > Exosome.

Shedding of the ectodomain produces a soluble form.
UniProt: P18827
Synonyms: CD138 Antibody
CD138 antigen Antibody
CD_antigen Antibody
heparan sulfate proteoglycan fibroblast growth factor receptor Antibody
SDC Antibody
Sdc1 Antibody
SDC1_HUMAN Antibody
SYND1 Antibody
Syndecan 1 Antibody
syndecan proteoglycan 1 Antibody

Product Code - SYND1.112-FITC
Size Price Quantity
100µg £429

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