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Anti-Synaptophysin Antibody (FITC)

FabGennix
SYN.112-FITC
Overview
Name: Anti-Synaptophysin Antibody (FITC)
Description: Rabbit polyclonal antibody to Synaptophysin (FITC)
Applications: CM, ELISA, ICC, IF, IHC, IMM, WB
Dilutions: Confocal Microscopy: 1:100; DB: 1:10,000; ELISA: 1:10,000; Immunocytochemistry: 1:100; Immunofluorescence: 1:100; Immunohistochemistry: 1:100; Immunoprecipitation: 1:125; Western Blot: 1:1,000
Reactivity: Chicken, Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid region 250-350 on human Synaptophysin protein.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: FITC
Concentration: 0.60-0.62 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Tissue Specificity: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Involvement in Disease: Mental retardation, X-linked, SYP-related: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.
Sequence Similarities: Belongs to the synaptophysin/synaptobrevin family.
Post-Translational Modification: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
Cellular Location: Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane. Cell junction > Synapse > Synaptosome.
UniProt: P08247
Synonyms: Major synaptic vesicle protein p38 Antibody
MRX96 Antibody
MRXSYP Antibody
Syn p38 Antibody
Syp Antibody
SYPH Antibody
SYPH_HUMAN Antibody
SypI Antibody

Product Code - SYN.112-FITC
Size Price Quantity
100µg £475

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