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Anti-GPCR GPR75 Antibody (FITC)

FabGennix
GPCR75.101-FITC
Overview
Name: Anti-GPCR GPR75 Antibody (FITC)
Description: Rabbit polyclonal antibody to GPCR GPR75 (FITC)
Applications: CM, ELISA, ICC, IHC, IF, IP, WB
Dilutions: Confocal Microscopy: 1:250; DB: 1:10,000; ELISA: 1:10,000; Immunocytochemistry: 1:250; Immunofluorescence: 1:250; Immunohistochemistry: 1:250; Immunoprecipitation: 1:250; Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid reigon 1-50 on human G protein-coupled receptor 75 protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: FITC
Concentration: 0.75-1.25 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Tissue Specificity: Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level).
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Cellular Location: Cell membrane.
UniProt: O95800
Synonyms: G protein coupled receptor 75 Antibody
GPR chr2 Antibody
Gpr75 Antibody
GPR75_HUMAN Antibody
GPRchr2 Antibody
OTTHUMP00000159608 Antibody
Probable G protein coupled receptor 75 Antibody
Probable G-protein coupled receptor 75 Antibody
WI 31133 Antibody
WI31133 Antibody

Product Code - GPCR75.101-FITC
Size Price Quantity
100µg £429

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