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Anti-Cytokeratin 7 Antibody (FITC)

Description: Rabbit polyclonal antibody to Cytokeratin 7 (FITC)
Category: Primary Antibodies
Applications: ELISA, IP, WB
Host: Rabbit
Clonality: Polyclonal
Conjugate: FITC
Reactivity: Human, Mouse, Rat
UniProt: P08729
Immunogen: Synthetic peptide taken within amino acid region 419-469 on human keratin, type II cytoskeletal 7 protein.
Concentration: 0.64-0.72 µg/µl in antibody stabilization buffer
Synonyms: CK 7 antibody
Background: Serves to block interferon-dependent interphase and stimulates DNA synthesis. Plays a role in the translational regulation of human papillomavirus type 16 E7 mRNA.
Storage: -20⁰C for long term storage
Accession No: NP_005547
Recommended Dilutions: DB: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:150; Western Blot: 1:500

Target (Information from UniProt)
Function: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Tissue Specificity: Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
Sequence Similarities: Belongs to the intermediate filament family.
Post-Translational Modification: Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
Cellular Location: Cytoplasm.

Product Code - CK7.721-FITC
Size Price Quantity
100µg £429

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