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Anti-SIGLEC10 Antibody (Biotin)

FabGennix
SIGLEC10-BIOTIN
Overview
Name: Anti-SIGLEC10 Antibody (Biotin)
Description: Rabbit polyclonal antibody to SIGLEC10 (Biotin)
Applications: ELISA, IP, WB
Dilutions: ELISA: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500; Western Blot: 1:500
Reactivity: Human, Rat
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Biotin
Concentration: 0.56-0.60 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Tissue Specificity: Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform 5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found at high levels and isoform 2 at lower levels in bone marrow, spleen and spinal chord. Isoform 2 is also found in brain. Isoform 4 is specifically found in natural killer cells.
Sequence Similarities: Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Post-Translational Modification: Phosphorylation of Tyr-667 is involved in binding to PTPN6.
Cellular Location: Cell membrane.
UniProt: Q96LC7
Synonyms: mSiglec G Antibody
PRO940 Antibody
Sialic acid binding Ig like lectin 10 Antibody
sialic acid binding Ig like lectin 10 Ig like lectin 7 Antibody
sialic acid binding Ig like lectin G Antibody
Sialic acid binding Immunoglobulin like lectin 10 Antibody
Sialic acid-binding Ig-like lectin 10 Antibody
SIG10_HUMAN Antibody
SIGLEC 10 Antibody
Siglec G Antibody
siglec like gene 2 Antibody
Siglec like protein 2 Antibody
Siglec-10 Antibody
Siglec-like protein 2 Antibody
Siglecg Antibody
SLG2 Antibody

Product Code - SIGLEC10-BIOTIN
Size Price Quantity
100µg £429

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