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Anti-S100 beta Antibody (Biotin)

FabGennix
S100B.n-BIOTIN
Details
Description: Rabbit polyclonal antibody to S100 beta (Biotin)
Category: Primary Antibodies
Applications: ELISA, WB
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Reactivity: Human, Rat
UniProt: P25815
Immunogen: N-epitope synthetic peptide corresponding to unique amino acid sequences on human S100 protein.
Concentration: 0.65 µg/µl in antibody stabilization buffer
Synonyms: NEF antibody
Background: May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
Storage: -20⁰C for long term storage
Recommended Dilutions: DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500

Target (Information from UniProt)
Function: May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
Tissue Specificity: Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
Sequence Similarities: Belongs to the S-100 family.
Cellular Location: Nucleus. Cytoplasm. Cell projection > Microvillus membrane.

Colocalizes with S100PBP in the nucleus. Colocolizes with EZR in the microvilli in a calcium-dependent manner.

Product Code - S100B.n-BIOTIN
Size Price Quantity
100µg £475

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