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Anti-Dopamine D5 Receptor (Biotin)

FabGennix
D5R.2-BIOTIN
Overview
Name: Anti-Dopamine D5 Receptor (Biotin)
Description: Rabbit polyclonal antibody to Dopamine D5 Receptor (Biotin)
Applications: ELISA, WB
Dilutions: DB: 1:50,000; DB: 1:50,000; ELISA: 1:50,000; Western Blot: 1:1,000-1:1,5000
Reactivity: Human, Monkey
Immunogen: Synthetic peptide corresponding to unique sequence on Dopamine Receptor D5 protein.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Biotin
Concentration: 0.5-1.5 µg/µl in antibody stabilization buffer
Storage: -20 ° C for long term storage

Target (Information from UniProt)
Function: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Tissue Specificity: Neuron-specific, localized primarily within limbic regions of the brain.
Involvement in Disease: Benign essential blepharospasm: A primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Cellular Location: Cell membrane.
UniProt: P21918
Synonyms: D(1B) dopamine receptor Antibody
D(5) dopamine receptor Antibody
D1 beta dopamine receptor Antibody
D1B dopamine receptor Antibody
D1beta dopamine receptor Antibody
D5 dopamine receptor Antibody
DBDR Antibody
Dopamine receptor D1B Antibody
Dopamine Receptor D5 Antibody
DRD 1B Antibody
DRD 5 Antibody
DRD1B Antibody
DRD1L2 Antibody
DRD5 Antibody
DRD5_HUMAN Antibody
MGC10601 Antibody

Product Code - D5R.2-BIOTIN
Size Price Quantity
100µg £429

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