phone icon
+44 (0)1223 298875

Anti-GTPase HRAS Antibody (FITC)

FabGennix
P21RAS-112-FITC
Overview
Name: Anti-GTPase HRAS Antibody (FITC)
Description: Rabbit polyclonal antibody to GTPase HRAS (FITC)
Applications: ELISA, IP, WB
Dilutions: ELISA: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:150; Western Blot: 1:500
Reactivity: Chicken, Human, Mouse
Immunogen: Synthetic peptide taken within amino acid region 100-150 on human GTPase HRAS protein.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: FITC
Concentration: 1.00-1.25 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Tissue Specificity: Widely expressed.
Involvement in Disease: Costello syndrome: A rare condition characterized by prenatally increased growth, postnatal growth deficiency, mental retardation, distinctive facial appearance, cardiovascular abnormalities (typically pulmonic stenosis, hypertrophic cardiomyopathy and/or atrial tachycardia), tumor predisposition, skin and musculoskeletal abnormalities.

Congenital myopathy with excess of muscle spindles: Variant of Costello syndrome.

Thyroid cancer, non-medullary, 2: A form of non-medullary thyroid cancer (NMTC), a cancer characterized by tumors originating from the thyroid follicular cells. NMTCs represent approximately 95% of all cases of thyroid cancer and are classified into papillary, follicular, Hurthle cell, and anaplastic neoplasms.

Bladder cancer: A malignancy originating in tissues of the urinary bladder. It often presents with multiple tumors appearing at different times and at different sites in the bladder. Most bladder cancers are transitional cell carcinomas that begin in cells that normally make up the inner lining of the bladder. Other types of bladder cancer include squamous cell carcinoma (cancer that begins in thin, flat cells) and adenocarcinoma (cancer that begins in cells that make and release mucus and other fluids). Bladder cancer is a complex disorder with both genetic and environmental influences.

Schimmelpenning-Feuerstein-Mims syndrome: A disease characterized by sebaceous nevi, often on the face, associated with variable ipsilateral abnormalities of the central nervous system, ocular anomalies, and skeletal defects. Many oral manifestations have been reported, not only including hypoplastic and malformed teeth, and mucosal papillomatosis, but also ankyloglossia, hemihyperplastic tongue, intraoral nevus, giant cell granuloma, ameloblastoma, bone cysts, follicular cysts, oligodontia, and odontodysplasia. Sebaceous nevi follow the lines of Blaschko and these can continue as linear intraoral lesions, as in mucosal papillomatosis.
Sequence Similarities: Belongs to the small GTPase superfamily. Ras family.
Post-Translational Modification: Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.
Cellular Location: Cell membrane. Cell membrane. Golgi apparatus. Golgi apparatus membrane.

The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form (By similarity). Shuttles between the plasma membrane and the Golgi apparatus.
UniProt: P01112
Synonyms: ALPS4 Antibody
C BAS/HAS Antibody
C H RAS Antibody
C HA RAS1 Antibody
C has/bas p21 protein Antibody
C K RAS Antibody
C ras Ki 2 activated oncogene Antibody
C-BAS/HAS Antibody
c-H-ras Antibody
C-HA-RAS1 Antibody
c-K-ras Antibody
c-Ki-ras Antibody
C-Kirsten-ras protein Antibody
Cellular c-Ki-ras2 proto-oncogene Antibody
CFC2 Antibody
CTLO Antibody
GTP and GDP binding peptide B Antibody
GTPase HRas, N-terminally processed Antibody
GTPase KRas Antibody
GTPase NRas Antibody
H Ras 1 Antibody
H RASIDX Antibody
H-Ras-1 Antibody
H-RASIDX Antibody
Ha Ras Antibody
Ha Ras1 proto oncoprotein Antibody
Ha-Ras Antibody
HAMSV Antibody
Harvey rat sarcoma viral oncogene homolog Antibody
Harvey rat sarcoma viral oncoprotein Antibody
HRAS Antibody
HRAS + KRAS Antibody
HRAS1 Antibody
K ras Antibody
K RAS2A Antibody
K RAS2B Antibody
K RAS4A Antibody
K RAS4B Antibody
K-RAS Antibody
K-Ras 2 Antibody
K-ras p21 protein Antibody
KI RAS Antibody
Ki-Ras Antibody
Kirsten rat sarcoma viral oncogene homolog Antibody
KRAS Antibody
KRAS+HRAS+NRAS Antibody
KRAS1 Antibody
KRAS2 Antibody
N ras Antibody
N ras + c Ha ras Antibody
N ras protein part 4 Antibody
N-RAS Antibody
N-terminally processed Antibody
Neuroblastoma RAS viral (v ras) oncogene homolog Antibody
Neuroblastoma RAS viral (v-ras) oncogene homolog Antibody
NRAS Antibody
NRAS1 Antibody
NS Antibody
NS3 Antibody
NS6 Antibody
Oncogene KRAS2 Antibody
p19 H RasIDX protein Antibody
p21ras Antibody
Pan Ras Antibody
PR310 c-K-ras oncogene Antibody
Ras Antibody
Ras family small GTP binding protein H Ras Antibody
RAS1 Antibody
RASH1 Antibody
RASH_HUMAN Antibody
RASK2 Antibody
Transformation gene oncogene HAMSV Antibody
Transformation gene: oncogene HAMSV Antibody
Transforming protein N Ras Antibody
Transforming protein N-Ras Antibody
Transforming protein p21 Antibody
V Ha ras Harvey rat sarcoma viral oncogene homolog Antibody
v Ki ras2 Kirsten rat sarcoma viral oncogene homolog Antibody
V ras neuroblastoma RAS viral oncogene homolog Antibody
V-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog Antibody
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog Antibody
VH Ras Antibody
vHa RAS Antibody

Product Code - P21RAS-112-FITC
Size Price Quantity
100µg £429

or
Request a quotation
Contact us directly to order
  • call icon +44 (0)1223 298875
  • +44 (0)1223 281447
  • email icon orders@ab-y-ss.com
Product Quality
  • guarantee icon
  • We promise guaranteed product quality
  • and expert customer service.
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe