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Anti-Human Lactoferrin Antibody (FITC)

FabGennix
HLAC-FITC
Overview
Name: Anti-Human Lactoferrin Antibody (FITC)
Description: Rabbit polyclonal antibody to Human Lactoferrin (FITC)
Applications: CM, ELISA, ICC, IF, IHC, IP, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Immunocytochemistry: 1:200; Immunofluorescence: 1:200; Immunohistochemistry: 1:200; Immunoprecipitation: 1:200; Western Blot: 1:500
Reactivity: Human
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: FITC
Concentration: 0.8 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
Tissue Specificity: High levels are found in saliva and tears, intermediate levels in serum and plasma, and low levels in urine. In kidney, detected in the distal collecting tubules in the medulla but not in the cortical region or in blood vessels. Detected in peripheral blood neutrophils (at protein level). Isoform 1 and isoform DeltaLf are expressed in breast, prostate, spleen, pancreas, kidney, small intestine, lung, skeletal muscle, uterus, thymus and fetal liver. Isoform 1 is expressed in brain, testis and peripheral blood leukocytes; isoform DeltaLf is barely detectable in these tissues. Isoform DeltaLf is expressed in placenta, liver and ovary; isoform 1 is barely detectable in these tissues. In kidney, isoform 1 is expressed at high levels in the collecting tubules of the medulla but at very low levels in the cortex.
Sequence Similarities: Belongs to the transferrin family.
Post-Translational Modification: Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391.
Cellular Location: Secreted. Cytoplasmic granule.

Secreted into most exocrine fluids by various endothelial cells. Stored in the secondary granules of neutrophils.
UniProt: P02788

Product Code - HLAC-FITC
Size Price Quantity
100µg £429

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