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Anti-Chimaerin beta 2 Antibody (FITC)

FabGennix
CHIM2-FITC
Overview
Name: Anti-Chimaerin beta 2 Antibody (FITC)
Description: Rabbit polyclonal antibody to Chimaerin beta 2 (FITC)
Applications: ELISA, IHC, IP, WB
Dilutions: Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid region 150-180 on beta 2-chimaerin protein.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: FITC
Concentration: 0.68-0.71 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
Tissue Specificity: Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
Cellular Location: Membrane.
UniProt: P52757

Product Code - CHIM2-FITC
Size Price Quantity
100µg £429

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