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Anti-Phospho-PGCA Antibody (Biotin)

FabGennix
PPGCA-BIOTIN
Overview
Name: Anti-Phospho-PGCA Antibody (Biotin)
Description: Rabbit polyclonal antibody to Phospho-PGCA (Biotin)
Applications: ELISA, IP, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:150; Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid region 500-550 on human Atrial natriuretic peptide receptor 1 protein.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Biotin
Concentration: 0.55-0.75 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Sequence Similarities: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Post-Translational Modification: Phosphorylation of the protein kinase-like domain is required for full activation by ANP.
Cellular Location: Membrane.
UniProt: P16066

Product Code - PPGCA-BIOTIN
Size Price Quantity
100µg £475

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