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Anti-Phospho-Smad1 Antibody (Biotin)

FabGennix
PMAD-BIOTIN
Overview
Name: Anti-Phospho-Smad1 Antibody (Biotin)
Description: Rabbit polyclonal antibody to Phospho-Smad1 (Biotin)
Applications: ELISA, WB
Dilutions: DB: 1:20,000-1:50,000; ELISA: 1:20,000-1:50,000; Western Blot: 1:500-1:1,000
Reactivity: Drosophila melanogaster
Immunogen: Synthetic peptide taken within amino acid region 405-455 on D. melanogaster Mothers against dpp protein.
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Biotin
Concentration: 0 .5-1.0 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Required for the function of decapentaplegic. May play an important role in mediating Dpp signaling. Involved in the BMP signaling pathway.
Sequence Similarities: Belongs to the dwarfin/SMAD family.
Post-Translational Modification: Phosphorylation on Ser-453 and/or Ser-455 is required for interaction with lack. Phosphorylation on Ser-25 by key/Nemo promotes export from nucleus and antagonizes BMP signaling.
Cellular Location: Cytoplasm. Nucleus.
UniProt: P42003

Product Code - PMAD-BIOTIN
Size Price Quantity
100µg £475

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