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Anti-Sialoadhesin Antibody (Biotin)

FabGennix
CD169-BIOTIN
Overview
Name: Anti-Sialoadhesin Antibody (Biotin)
Description: Rabbit polyclonal antibody to Sialoadhesin (Biotin)
Applications: ELISA, IP, WB
Dilutions: ELISA: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:200; Western Blot: 1:500
Reactivity: Human, Monkey
Immunogen: Synthetic peptide taken within amino acid region 10-60 on human Sialoadhesin protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Concentration: 0.5 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target (Information from UniProt)
Function: Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.
Tissue Specificity: Expressed by macrophages in various tissues. High levels are found in spleen, lymph node, perivascular macrophages in brain and lower levels in bone marrow, liver Kupffer cells and lamina propria of colon and lung. Also expressed by inflammatory macrophages in rheumatoid arthritis.
Sequence Similarities: Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Cellular Location: Cell membrane.
UniProt: Q9BZZ2
Synonyms: CD169 Antibody
CD169 antigen Antibody
dJ1009E24.1 Antibody
DKFZp667F058 Antibody
FLJ00051 Antibody
FLJ00055 Antibody
FLJ00073 Antibody
FLJ00411 Antibody
FLJ32150 Antibody
Sialic acid binding Ig like lectin 1 Antibody
sialic acid binding Ig-like lectin 1, sialoadhesin Antibody
Sialic acid binding immunoglobulin like lectin 1 Antibody
Sialic acid-binding Ig-like lectin 1 Antibody
Siglec 1 Antibody
Siglec-1 Antibody
Siglec1 Antibody
SN Antibody
SN_HUMAN Antibody

Product Code - CD169-BIOTIN
Size Price Quantity
100µg £429

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