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Anti-Prostaglandin E Receptor EP2 Antibody (Biotin)

FabGennix
EP3.2-BIOTIN
Details
Description: Rabbit polyclonal antibody to Prostaglandin E Receptor EP2 (Biotin)
Category: Primary Antibodies
Applications: CM, ELISA, ICC, IF, IHC, IMM, WB
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Reactivity: Human
UniProt: P43115
Immunogen: Synthetic peptide corresponding to unique amino acid sequence on Prostaglandin 2 Receptor type 2 protein.
Concentration: 0.5-0.6 µg/µl in antibody stabilization buffer
Synonyms: EP 2 antibody
Background: Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
Storage: -20⁰C for long term storage
Accession No: NP_942010.1
Recommended Dilutions: Confocal Microscopy: 1:250; DB: 1:10,000; ELISA: 1:10,000; Immunocytochemistry: 1:250; Immunofluorescence: 1:250; Immunohistochemistry: 1:250; Immunoprecipitation: 1:250; Western Blot: 1:500

Target (Information from UniProt)
Function: Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
Tissue Specificity: Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Cellular Location: Cell membrane.

Product Code - EP3.2-BIOTIN
Size Price Quantity
100µg £429

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