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Anti-IgE Antibody (HRP)

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Absea Biotechnology
Description: Mouse monoclonal (1A2) antibody to IgE (HRP)
Category: Primary Antibodies
Applications: sELISA
Host: Mouse
Clonality: Monoclonal
Clone: 1A2
Isotype: IgG1
Conjugate: HRP
UniProt: P01854
Antigen: IgE
Antigen Species: Human
Uniprot Protein Name: Ig epsilon chain C region
Uniprot Gene Name: Name: IGHE
Sequence: Recombinant human IgE containing the constant regions of the heavy chain.

Target (Information from UniProt)
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.

Product Code - 000101A02H
Size Price Quantity
100µg £186
200µg £273
1mg £730

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