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Anti-Growth Hormone Antibody

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Absea Biotechnology
011303G12
Overview
Name: Anti-Growth Hormone Antibody
Description: Rat monoclonal (KT34) antibody to Growth hormone.
Applications: WB, ELISA
Reactivity: Human
Immunogen: Recombinant human growth hormone.
Host: Rat
Clonality: Monoclonal
Clone: KT34
Isotype: IgG2a
Conjugate: Unconjugated
Purification: IgG is purified through a Protein G column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target (Information from UniProt)
Function: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Involvement in Disease: Growth hormone deficiency, isolated, 1A: An autosomal recessive, severe deficiency of growth hormone leading to dwarfism. Patients often develop antibodies to administered growth hormone.

Growth hormone deficiency, isolated, 1B: An autosomal recessive deficiency of growth hormone leading to short stature. Patients have low but detectable levels of growth hormone, significantly retarded bone age, and a positive response and immunologic tolerance to growth hormone therapy.

Kowarski syndrome: A syndrome clinically characterized by short stature associated with bioinactive growth hormone, normal or slightly increased growth hormone secretion, pathologically low insulin-like growth factor 1 levels, and normal catch-up growth on growth hormone replacement therapy.

Growth hormone deficiency, isolated, 2: An autosomal dominant deficiency of growth hormone leading to short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy.
Sequence Similarities: Belongs to the somatotropin/prolactin family.
Cellular Location: Secreted.
UniProt: P01241
Gene ID: 2688
Synonyms: gH Antibody
GH-N Antibody
GH1 Antibody
GHN Antibody
Growth hormone 1 Antibody
Growth hormone, normal Antibody
Growth hormone, pituitary Antibody
HG1 Antibody
hGH-N Antibody
IGHD1B Antibody
Pituitary growth hormone Antibody
RNGHGP Antibody
Somatotropin Antibody
SOMA_HUMAN Antibody

Product Code - 011303G12
Size Price Quantity
100µg £178
200µg £259
1mg £682

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