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Anti-Growth Hormone Antibody

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Absea Biotechnology
011303G12
Details
Description: Rat monoclonal (KT34) antibody to Growth hormone
Category: Primary Antibodies
Applications: WB, ELISA
Host: Rat
Clonality: Monoclonal
Clone: KT34
Isotype: IgG2a
Conjugate: Unconjugated
UniProt: P01241
Gene ID: 2688
Antigen: Growth hormone
Antigen Species: Human
Uniprot Protein Name: Recommended name: Somatotropin Alternative name(s): Growth hormone
Uniprot Gene Name: Name: GH1
Amino Acid Start: 1
Amino Acid End: 217
Protein Length: 217

Target (Information from UniProt)
Function: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Involvement in Disease: Growth hormone deficiency, isolated, 1A: An autosomal recessive, severe deficiency of growth hormone leading to dwarfism. Patients often develop antibodies to administered growth hormone.

Growth hormone deficiency, isolated, 1B: An autosomal recessive deficiency of growth hormone leading to short stature. Patients have low but detectable levels of growth hormone, significantly retarded bone age, and a positive response and immunologic tolerance to growth hormone therapy.

Kowarski syndrome: A syndrome clinically characterized by short stature associated with bioinactive growth hormone, normal or slightly increased growth hormone secretion, pathologically low insulin-like growth factor 1 levels, and normal catch-up growth on growth hormone replacement therapy.

Growth hormone deficiency, isolated, 2: An autosomal dominant deficiency of growth hormone leading to short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy.
Sequence Similarities: Belongs to the somatotropin/prolactin family.
Cellular Location: Secreted.

Product Code - 011303G12
Size Price Quantity
100µg £178
200µg £259
1mg £682

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