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Anti-IgE Antibody

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Absea Biotechnology
000101A02
Overview
Name: Anti-IgE Antibody
Description: Mouse monoclonal (1A2) antibody to IgE
Applications: ELISA, WB
Antigen: IgE
Sequence: Recombinant human IgE containing the constant regions of the heavy chain.
Host: Mouse
Clonality: Monoclonal
Clone: 1A2
Isotype: IgG1
Conjugate: Unconjugated

Target (Information from UniProt)
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.
UniProt: P01854
Synonyms: Igh2 Antibody
IGHE Antibody
IGHEP1 Antibody
Immunoglobulin heavy constant epsilon Antibody

Product Code - 000101A02
Size Price Quantity
100µg £178
200µg £259
1mg £682

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