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Anti-GP IIb/IIIa Antibody

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Name: Anti-GP IIb/IIIa Antibody
Description: Mouse monoclonal antibody to GP IIb/IIIa
Specificity: The mAb is reactive to platelet coated ELISA plate.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Human platelet suspension
Host: Mouse
Clonality: Monoclonal
Clone: 71
Isotype: IgG1
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Introduction: Human platelet membrane glycoprotein Glycoprotein IIb/IIIa (GP IIb/IIIa) is a dominate receptor on the platelet membrane with very high molecular weight (>200kDa). After the platelet is activated, the GP IIb/IIIa receptor complex changes conformation and binds to fibrinogen in blood circulation with high affinity. The activation of platelets is initiated locally when the endothelial layer is wounded and the platelets are exposed to the collagen underneath the endothelium. The fibrinogen aggregates with platelets when binding to the GP IIb/IIIa receptor on platelets, thus primary haemostasis (Platelet clot) is formed.

Product Code - MO-M40040Q
Size Price Quantity
100µg £267
500µg £368

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