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Anti-HCV NS-3 Antibody

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Name: Anti-HCV NS-3 Antibody
Description: Mouse monoclonal antibody to HCV NS-3
Specificity: mAb 5 reacts with recombinant NS-3 (residues 1252-1477 on HCV polyprotein) and recombinant chimeric HCV polyprotein (60 kDa.)
Applications: ELISA, WB
Reactivity: Human hepatitis C virus
Cross Reactivity: No cross reaction can be seen with recombinant core protein C + envelop protein M (residues 1-142), synthetic core protein C (residues 1-61), synthetic NS-3 protein (residues 1378-1458) and synthetic NS-4a protein (residues 1689-1735).
Immunogen: Purified recombinant chimeric HCV polyprotein (555 amino acid residues)
Host: Mouse
Clonality: Monoclonal
Clone: 5
Isotype: IgG1
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Introduction: Hepatitis C virus (HCV) causes chronic hepatitis and liver cirrhosis in human through blood and body fluid transmission. HCV has a positive sense single RNA genome enclosed in the nucleocapsid made of core protein (capsid protein). The nucleocapsid is covered by an envelope made of lipoproteins (E1 and E2). The 9.6 kb HCV genome has a single open-reading frame, which is to be translated into a single polyprotein. HCV viral proteins are produced after processing the polyprotein. Genes for core protein and envelop proteins are located adjacently at the 5’-end of HCV genome, followed by genes for non-structural proteins including NS2, NS3, NS4A, NS4B, NS5, NS5A and NS5B.

Product Code - MO-I40018L
Size Price Quantity
500µg £358

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