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Anti-HCV NS-4 Antibody

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Name: Anti-HCV NS-4 Antibody
Description: Mouse monoclonal antibody to HCV NS-4
Specificity: mAb 7B7/5G9 is reactive with Synthetic NS-4a (residues 1689-1735 on HCV polyprotein) and recombinant chimeric HCV (60 kDa).
Applications: ELISA, WB
Reactivity: Human hepatitis C virus
Cross Reactivity: No cross reaction can be seen with HCV core region and other non-structural regions.
Immunogen: Synthetic polypeptide in which overlapping sequence of at least 90 residues in length were selected from immunodominant NS-4 region of Chinese HCV strains.
Host: Mouse
Clonality: Monoclonal
Clone: 7B7/5G9
Isotype: IgG1
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Introduction: Hepatitis C virus (HCV) causes chronic hepatitis and liver cirrhosis in human through blood and body fluid transmission. HCV has a positive sense single RNA genome enclosed in the nucleocapsid made of core protein (capsid protein). The nucleocapsid is covered by an envelope made of lipoproteins (E1 and E2). The 9.6 kb HCV genome has a single open-reading frame, which is to be translated into a single polyprotein. HCV viral proteins are produced after processing the polyprotein. Genes for core protein and envelop proteins are located adjacently at the 5’-end of HCV genome, followed by genes for non-structural proteins including NS2, NS3, NS4A, NS4B, NS5, NS5A and NS5B.

Product Code - MO-I40016B
Size Price Quantity
500µg £358

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