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Anti-MCP-3 Antibody

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Name: Anti-MCP-3 Antibody
Description: Mouse monoclonal antibody to MCP-3
Specificity: Reactive with natural and recombinant human MCP-3
Applications: ELISA, WB
Reactivity: Human
Cross Reactivity: Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1β, IL-8, MCAF, SAA and EGF.
Immunogen: Recombinant human MCP-3 (M.W. 8.5kDa containing 76 amino acids residues)
Host: Mouse
Clonality: Monoclonal
Clone: 113
Isotype: IgG1
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2.

Introduction: Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78% sequence homology with MCP-1 and 58% sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.
Synonyms: C-C motif chemokine 7 Antibody
Ccl7 Antibody
CCL7_HUMAN Antibody
Chemokine CC motif ligand 7 Antibody
FIC Antibody
MARC Antibody
MCP3 Antibody
Monocyte chemoattractant protein 3 Antibody
Monocyte chemotactic protein 3 Antibody
NC28 Antibody
RP23-350G1.4 Antibody
SCYA6 Antibody
SCYA7 Antibody
Small-inducible cytokine A7 Antibody

Product Code - MO-C40088A
Size Price Quantity
100µg £267
500µg £388

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