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Anti-IL-1β Antibody

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Name: Anti-IL-1β Antibody
Description: Mouse monoclonal antibody to human Interleukin-1 beta (IL-1β)
Specificity: Reactive with natural and recombinant human IL-1β
Applications: ELISA, WB
Reactivity: Human
Cross Reactivity: Does not show any cross reaction with recombinant human IL-1α, recombinant murine IL-1α or IL-1β.
Immunogen: Purified recombinant human IL-1β
Host: Mouse
Clonality: Monoclonal
Clone: S1H12
Isotype: IgG1
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2.

Introduction: Interleukin 1β (IL-1β) shares the IL-1 receptor with other cytokines in IL-1 family. It is primarily produced by activated macrophage as a proprotein, which is cleaved by caspase I to become active. Like IL-1α, IL-1β is an important mediator of innate immunity. IL-1β stimulates lymphocyte proliferation and the production of TNF-α, IL-6 and IL-8. IL-1β and TNF-α can synergically act at NFkB and mitogen kinases including JNKs and p38 MARKs, thus leading to the selective expression of genes for immunity and inflammation.

Product Code - MO-C40029A
Size Price Quantity
100µg £267
500µg £388

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