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Anti-p383-ELK-1 Antibody

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Name: Anti-p383-ELK-1 Antibody
Description: Mouse monoclonal antibody to p383-ELK-1
Specificity: Reactive to serine383 phosphorylated human ELK-1 peptide fragment conjugated with KLH or the peptide-BSA conjugate. Not reactive to un-conjugated serine383 phosphorylated human ELK-1 peptide, KLH or BSA.
Applications: ELISA
Reactivity: Human
Immunogen: A serine383 phosphorylated human ELK-1 peptide fragment conjugated with KLH
Host: Mouse
Clonality: Monoclonal
Clone: B4A12
Isotype: IgG1
Formulation: Lyophilized form from a solution of 0.01M PBS, pH7.0

Introduction: ELK1 belongs to the EST transcription factor family. Proteins in the family have a unique DNA binding domain that binds to conserved DNA sequences. Phosphorylation of ELK1 at Serine 383 and 389 by mitogen-activated protein kinases (MAPKs) activates ELK1. The binding of ELK1 to target sequences is also regulated by its co-factor, serum response factor (SRF), by alternative splicing, and by SUMOylation. ELK1 regulates the transcription of c-fos and genes encoding cytoskeleton proteins, and was found to play a role in long-term memory formation, drug addiction and other neurological disorders.

Product Code - MO-P40002A
Size Price Quantity
100µg £297
500µg £448

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