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Anti-CRP Antibody

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Name: Anti-CRP Antibody
Description: Mouse monoclonal antibody to CRP
Applications: ELISA
Reactivity: Human
Cross Reactivity: No detectable cross-reaction with human normal serum proteins.
Immunogen: Purified CRP from human pleural fluid
Host: Mouse
Clonality: Monoclonal
Clone: 63F4
Isotype: IgG1
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.0

Introduction: C-reactive protein (CRP) is an acute phase protein that is comprised of five identical 23kDa subunits. The protein increases rapidly in response to inflammation, trauma and infection, and drops to normal level when the conditions no longer present. CRP plays a role in innate immunity by binding to phosphachlolin on the surface of damaged cells or certain microbes, and activating the C1q complex in complement system. CRP is primarily produced by hepatocytes under the stimulation by inflammatory cytokines including IL-6 and TNF-alpha. Elevated CRP level is implicated with bacterial infection, autoimmune diseases, trauma and post-surgical complications. Study has shown that people with higher CRP baseline have a higher disposition to develop cardiovascular diseases such as heart attack and stroke.
Synonyms: Pentraxin 1, short Antibody
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CRP_HUMAN Antibody
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OTTHUMP00000020657 Antibody
OTTHUMP00000020658 Antibody
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Product Code - MO-M40023A
Size Price Quantity
100µg £206
500µg £317

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