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Anti-IFN-γ Antibody

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Anogen
MO-C40004D
Overview
Name: Anti-IFN-γ Antibody
Description: Mouse monoclonal antibody to human Interferon-gamma (IFN-γ)
Specificity: This antibody recognizes both recombinant and native human IFN-γ.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Purified recombinant human IFN-γ
Host: Mouse
Clonality: Monoclonal
Clone: 315
Isotype: IgG1
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.0

Target
Introduction: IFN-γ is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL), effector T cells once antigen-specific immunity develops. IFN-γ stimulates its own expression and up-regulates other genes to stimulate and modulate immunity mainly through the Jak-Stat signalling pathway. It promoters T helper 1 differentiation and cell associated immunity, and also suppresses T helper 2 differentiation and humoral immunity. IFN-γ is a potent macrophage activator. It binds to macrophage in conjugation with CD40, causing the macrophage to produce elevated amounts of MHC molecules. It also stimulates the production of antigen-processing associated transporters and enzymes. IFN-γ is critical for anti-tumour and anti-viral immunity.

Product Code - MO-C40004D
Size Price Quantity
100µg £267
500µg £388

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