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Anti-HCV NS-4 Antibody

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Anogen
MO-I40016J
Overview
Name: Anti-HCV NS-4 Antibody
Description: Mouse monoclonal antibody to HCV NS-4
Specificity: The mAb reacts with synthetic NS-4a protein (residues 1689-1735 on HCV polyprotein) and recombinant chimeric HCV polyprotein (60 kDa).
Applications: ELISA
Reactivity: Human hepatitis C virus
Cross Reactivity: No cross reaction was seen with recombinant core protein C + envelope protein M (residues 1-142), synthetic core protein C (residues 1 -61), recombinant NS-3 protein (residues 1252 -1477) and synthetic NS-3 protein (residues 1378-1458)
Immunogen: Purified recombinant chimeric HCV polyprotein (555 amino acid residues)
Host: Mouse
Clonality: Monoclonal
Clone: 202
Isotype: IgA
Formulation: Lyophilized

Target
Introduction: Hepatitis C virus (HCV) causes chronic hepatitis and liver cirrhosis in human through blood and body fluid transmission. HCV has a positive sense single RNA genome enclosed in the nucleocapsid made of core protein (capsid protein). The nucleocapsid is covered by an envelope made of lipoproteins (E1 and E2). The 9.6 kb HCV genome has a single open-reading frame, which is to be translated into a single polyprotein. HCV viral proteins are produced after processing the polyprotein. Genes for core protein and envelop proteins are located adjacently at the 5’-end of HCV genome, followed by genes for non-structural proteins including NS2, NS3, NS4A, NS4B, NS5, NS5A and NS5B.

Product Code - MO-I40016J
Size Price Quantity
500µg £358

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