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Anti-IDN3 (Delangin) Isoform A Antibody

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Absea Biotechnology
010702F01
Overview
Name: Anti-IDN3 (Delangin) Isoform A Antibody
Description: Rat monoclonal (KT54) antibody to IDN3 isoform A.
Applications: WB, IP, IF 
Reactivity: Human, Mouse
Immunogen: Delangin peptide coupled to carrier protein.
Amino Acid Start: 177
Amino Acid End: 420
Host: Rat
Clonality: Monoclonal
Clone: KT54
Isotype: IgG1
Conjugate: Unconjugated
Purification: Antibody is purified from culture supernatant using a protein G column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target (Information from UniProt)
Function: Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity).
Tissue Specificity: Widely expressed. Highly expressed in heart, skeletal muscle, fetal and adult liver, fetal and adult kidney. Expressed at intermediates level in thymus, placenta, peripheral leukocyte and small intestine. Weakly or not expressed in brain, colon, spleen and lung.
Involvement in Disease: Cornelia de Lange syndrome 1: A form of Cornelia de Lange syndrome, a clinically heterogeneous developmental disorder associated with malformations affecting multiple systems. Characterized by facial dysmorphisms, abnormal hands and feet, growth delay, cognitive retardation, hirsutism, gastroesophageal dysfunction and cardiac, ophthalmologic and genitourinary anomalies.
Sequence Similarities: Belongs to the SCC2/Nipped-B family.
Cellular Location: Nucleus.
UniProt: Q6KC79
Gene ID: 25836
Synonyms: CDLS Antibody
Colon tumor susceptibility 2 Antibody
Delangin Antibody
DKFZp434L1319 Antibody
FLJ11203 Antibody
FLJ12597 Antibody
FLJ13354 Antibody
FLJ13648 Antibody
FLJ44854 Antibody
IDN 3 Antibody
IDN 3 protein Antibody
IDN 3 protein isoform A Antibody
IDN 3 protein isoform B Antibody
IDN 3B Antibody
IDN3 B Antibody
IDN3 protein Antibody
IDN3 protein isoform A Antibody
IDN3 protein isoform B Antibody
IDN3B Antibody
Mis 4 Antibody
Mis4 Antibody
Nipbl Antibody
NIPBL_HUMAN Antibody
Nipped B homolog Antibody
Nipped B homolog (Drosophila) Antibody
Nipped B like Antibody
Nipped B like protein Antibody
Nipped-B-like protein Antibody
Scc 2 Antibody
SCC 2 homolog Antibody
Scc2 Antibody
SCC2 homolog Antibody
Sister chromatid cohesion protein Mis4 Antibody

Product Citations

Zuin J et al. A cohesin-independent role for NIPBL at promoters provides insights in CdLS. PLoS Genet 10(2): e1004153 (2014)

Seitan VC et al. Metazoan Scc4 Homologs Link Sister Chromatid Cohesion to Cell and Axon Migration Guidance. PLoS Biol. 4(8): e242 (2006).


Product Code - 010702F01
Size Price Quantity
100µg £186
200µg £273
1mg £730

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