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Anti-MAPRE3 (EB3) Antibody

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Absea Biotechnology
Description: Rat monoclonal (KT53) antibody to MAPRE3 (EB3)
Category: Primary Antibodies
Applications: WB, IP
Host: Rat
Clonality: Monoclonal
Clone: KT53
Isotype: IgG2a
Conjugate: Unconjugated
UniProt: Q9UPY8
Gene ID: 22924
Antigen: MAPRE3 (EB3)
Antigen Species: Human
Uniprot Protein Name: Microtubule-associated protein RP/EB family member 3 Short name=EB3
Uniprot Gene Name: Name: MAPRE3
Amino Acid Start: 1
Amino Acid End: 281
Protein Length: 281
Sequence: Nm_012326, nt 154-999.

Target (Information from UniProt)
Function: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
Tissue Specificity: Predominantly expressed in brain and muscle.
Sequence Similarities: Belongs to the MAPRE family.
Cellular Location: Cytoplasm > Cytoskeleton.

Associated with the microtubule network. Detected at the plus end of microtubules.

Product Citations

Komorova Y et al. Mammalian end binding proteins control persistent microtubule growth. J Cell Biol 184(5): 691-706 (2009)

Komarova Y et al. EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol. Biol. Cell. 16(11): 5334-45 (2005)

Product Code - 010320D02
Size Price Quantity
100µg £186
200µg £273
1mg £730

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