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Anti-MAPRE3 (EB3) Antibody

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Absea Biotechnology
Name: Anti-MAPRE3 (EB3) Antibody
Description: Rat monoclonal (KT53) antibody to MAPRE3 (EB3).
Applications: WB, IP
Reactivity: Human
Immunogen: Expressed human EB3 fragment.
Amino Acid Start: 177
Amino Acid End: 420
Host: Rat
Clonality: Monoclonal
Clone: KT53
Isotype: IgG2a
Conjugate: Unconjugated
Purification: Antibody is purified from culture supernatant using a protein G column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target (Information from UniProt)
Function: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
Tissue Specificity: Predominantly expressed in brain and muscle.
Sequence Similarities: Belongs to the MAPRE family.
Cellular Location: Cytoplasm > Cytoskeleton.

Associated with the microtubule network. Detected at the plus end of microtubules.
UniProt: Q9UPY8
Gene ID: 22924
Synonyms: 5530600P05Rik Antibody
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End binding protein 1 Antibody
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fa01e12 Antibody
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Microtubule Associated Protein Antibody
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Microtubule associated protein RP/EB family member 3 Antibody
Microtubule-associated protein RP/EB family member 1 Antibody
Microtubule-associated protein RP/EB family member 3 Antibody
OTTHUMP00000200910 Antibody
RP 3 Antibody
RP/EB Family Antibody
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wu:fa01e12 Antibody
wu:fc23e11 Antibody
wu:fi33c06 Antibody
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zgc:77807 Antibody
zgc:85755 Antibody

Product Citations

Komorova Y et al. Mammalian end binding proteins control persistent microtubule growth. J Cell Biol 184(5): 691-706 (2009)

Komarova Y et al. EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol. Biol. Cell. 16(11): 5334-45 (2005)

Product Code - 010320D02
Size Price Quantity
100µg £186
200µg £273
1mg £730

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