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Anti-AFP Antibody

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Absea Biotechnology
069203C11
Details
Description: Mouse monoclonal (KT137) antibody to AFP
Category: Primary Antibodies
Applications: sELISA
Host: Mouse
Clonality: Monoclonal
Clone: KT137
Isotype: IgG1
Conjugate: Unconjugated
UniProt: P02771
Gene ID: 174
Antigen: AFP
Antigen Species: Human
Uniprot Protein Name: Alpha-fetoprotein
Uniprot Gene Name: AFP
Sequence: Native human AFP purified from cord blood.

Target (Information from UniProt)
Function: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Tissue Specificity: Plasma. Synthesized by the fetal liver and yolk sac.
Involvement in Disease: Alpha-fetoprotein deficiency: A benign condition characterized by undetectable AFP levels in the amniotic fluid. Affected individuals are asymptomatic and present normal development.

Alpha-fetoprotein, hereditary persistence: A benign autosomal dominant condition characterized by continued expression of alpha-fetoprotein in adult life.
Sequence Similarities: Belongs to the ALB/AFP/VDB family.
Post-Translational Modification: Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
Cellular Location: Secreted.

Product Code - 069203C11
Size Price Quantity
100µg £178
200µg £259
1mg £682

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