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Anti-IgG3 Antibody (HRP)

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Absea Biotechnology
Name: Anti-IgG3 Antibody (HRP)
Description: Mouse monoclonal (KT133) antibody to IgG3 (HRP)
Applications: ELISA
Antigen: IgG3
Host: Mouse
Clonality: Monoclonal
Clone: KT133
Isotype: IgG1
Conjugate: HRP

Target (Information from UniProt)
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.
UniProt: P01860
Synonyms: DKFZp686H11213 Antibody
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Product Code - 068909H08H
Size Price Quantity
100µg £186
200µg £273
1mg £730

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